Comparing CBD Delivery Systems to confirm Bioavailablity otherwise Known as Efficacy. Why does it matter how YOU intake CBD?
What is Bioavailability?
Bioavailability is a term used in pharmacology, nutritional and environmental sciences referring to the degree and rate at which an administered compound is absorbed by the body’s circulatory system. When a compound is highly bioavailable, the body can absorb a large percentage of it consistently. Method of administration plays a crucial role in bioavailability. Recent years have produced an upward trend in the sublingual administration of compounds due to the high rate of bioavailability it allows. However, a new patented technology is now available that provides a more effective bioavailble solution.
Considered to be close to 100% effective way to receive all of the available nutrients, intravenous administration is the standard measurement for bioavailability; however, this method is very invasive and does inspire people to receive injections. Therefore, this route of administration is not reasonable for all compounds, nor is it practical for health reasons. The current available delivery systems can range anywhere between 15-95% absorption into the blood stream. Which method works best for you and your lifestyle is the question you have to ask yourself.
Methods of Administration
The most common way to receive substances into the body is through ingestion (aka eating and drinking). It is not always the most efficient method, but the vast majority of our daily intake is processed through this route.
Oral Intake ” Edibles”
When you eat, drink or swallow a pill, those compounds travel through the entire gastrointestinal tract. This journey starts in the stomach where acid, bile and other enzymes contribute to the breakdown. Then onto the intestines where absorption takes place and the liver where metabolization and distribution occur. Oral absorption rates ranges between only 10-20%.
The effects of the gastrointestinal tract are designed to be harsh. This is the system through which food is broken down and nutrients are stripped out. The process is called “first-metabolism.” Compounds make a second pass through the liver before they are eliminated. There are several factors that could impair oral uptake:
- High water solubility
- Not dissolving sufficiently
- Poor digestion
- Binding to other substances
- Use by intestinal bacteria
The word “sub” means under. “Lingual” refers to the tongue.” Sublingual administration involves placing a substance under the tongue, allowing it to dissolve and absorb through that tissue. The mucous membranes located under the tongue is ideal for absorption due to the large number of capillaries and blood vessels located there. Sublingual absorption rates ranges between 30-40%.
There are a number of uses for sublingual administration. It has been used to administer medicine, supplements and most recently CBD. Many CBD providers are looking for alternative sublingual delivery methods such as pills, tablets and even strips that dissolve under the tongue. Until recently sublingual administration was considered one of the the most effective way to deliver cannabinoids into the bloodstream.
Breathe it in ” Vaping or Smoking”
Inhalation is also a viable method to receive compounds into the bloodstream. Lung tissue has high permeability as well as a large absorptive surface area. The blood supply in the lungs is also sufficient to allow breathable compounds to enter systemic circulation. This makes inhalation a decent option to receive benefits and is generally superior to oral intake, but not as effective as sublingual or oral micro spray . Unfortunately, heating CBD will lower the efficacy of the product which means they can only use low temp devices to vape with. Inhalation absorption rates only range between 20-30%.
CBD Sublingual Administration ” Tincure”
Though edibles infused with CBD oil may be delicious and smoking may be a tradition, CBD sublingual administration is most commonly used. This means that you can take less of the substance sublingually and receive equal or greater effects because the compounds remain intact when entering the bloodstream.
Unfortunately, there are a number of issues with the tincure sublingual delivery system:
- Must leave under the tongue from 30 seconds to two minutes to receive maximum absorption
- It leaves an oily taste and feeling in your mouth
- Women do not like to store in their purse due to possible leakage issues
- It’s not socially acceptable to drip oil in your mouth in public; tincures/dropper bottles were meant for ears and your eyes.
- It’s very difficult to meter the dosage you take
- It’s difficult to transport due to lack of TSA approval
- Only 40% absorption occurs when leaving over 1 minute, only 30% if not.
For proper CBD sublingual use, place your desired amount of CBD tincture under the tongue and leave it there without swallowing for 1-2 minutes. The longer you can wait and allow the oil to be absorbed by the mucous membranes under the tongue, the more effective your dose will be.
CBD Oral Micro Spray Administration ” Patented technology”
CBD Oral Micro Spray Mist administration provides far more bioavailability than any other method. The CBD Micro Spray Mist is about 2.5x of a tincure at ~ 90% absorption rate into the body which means that you can take less of the substance orally and receive greater effects because the compounds remain intact when entering the bloodstream.
For proper CBD Oral Micro Spray use, spray the mist directly in the mouth or side of the cheek and leave it there without swallowing for about 30 seconds. The longer you can wait and allow it to be absorbed by the mucous membranes in the mouth, the more effective your dose will be.
Our lab can emulsify just about any element such as B12 and D3, DHA and supplements like melatonin, pain medication, caffeine and thousands of other supplements with CBD in just about any flavor you can think of, except for fiber and minerals.
The difference between a normal spray bottle and our patented emulsification suspension technology, is that our Micro Mist Spray shown above does not leak or clog. In addition, our technology provides 240 metered dosage sprays, while a normal spray bottle doe not have the ability to emulsify the liquid and the oil.
Destined to Replace all vape , tincture , capsule and edible products Click here to learn more about our patented revolutionary delivery system.
CBD can be used topically. CBD binds to CB2 receptors in the body, inhibiting production of the enzyme that breaks down the neurotransmitter called anandamide. The purpose of anandamide is to block pain receptors. More anandamide leads to less pain. Typically CBD infused pain creams and patches are becoming more and more popular pain relief.
CBD Oral Mist Spray is Number One
There are many great reasons to take CBD oil. Regardless of your individual motive, getting the most out of every dose makes a lot of sense. Using CBD Mirco Spray applications with a high-quality product is the best way to accomplish that purpose. Contact us to learn more about this revolutionary delivery system.